WE NEED BEEF INSULIN DIABETIC DEATH RATES CONTINUE TO RISE SINCE SYNTHETIC INSULIN Hit the Market 20 Years Ago. To Print: set printer for landscape. 25 years of diabetic deaths compared to the other death rates 1979-2002. 4 year diabetic deaths before synthetic insulins 16 yr diab death 4 yr diab deaths (no beef) 20 yr diab dead 1982    34600 1998    64800 2002    73,100 2002    73100 1979    33200 1983    36200 1999    68,400 1983    36200 Up   1400  4.2% Up  28,600   79% Up 4,700   6.9% Up 36900   102% Compare 4.2% to 3.1%                    then                      Compare 102% to 21.3% 4yr all deaths 16 Yr all deaths 4 yr all deaths 20 yr all death 1982   1.975M 1998   2.34M 2002   2.45M 2002 2.45M 1979    1.914M 1983   2.02M 1999   2.39M 1983    2.02 up 61,000>    3.1% Up 320,000 16% UP 60,000   2.5% Up 430,000  21.3% 20 yr population growth = 23% 1980 227,259,000 2000 281,422,000 Growth 54,163,000 = 23% 2004 population 294,415,000 TABLE OF CONTENTS: Statistics     Introduction:     Brief          Facts in a Nutshell        Male Deaths Highest ever recorded           Animal vs. Human Insulin      Other Realities        CDC’s counting methods changed          Percentages and costs           Heart failure up 244% for diabetics down for others          41% now experience hypoglycemic unawareness          100 people surveyed          Beef Insulin - Only One Shot Daily     History & New Science        Old Statement vs. New Statement        import beef insulin.4         GE synthetic insulins vs. Beef Insulin Death Rates     Margie Baker’s 60 Year Insulin History        Animal vs. Human Insulin Charts Insulin Policy     Now in effect     Requested change SUMMARY     Hypo Unawareness? Heart Failure?     Rocket Science     Unreasonable 102% death increase     Formula     Dr. Banting‘s, history     The Slate     Poor Man’s Pump     Only One Shot Daily    CANARYS in the MINE SHAFT Sources and Footnotes __________________________________________________________________ Introduction: Included are 2 newly disclosed scientific facts with Lilly and Novo statements concerning synthetic insulins (animal vs synthetic insulin implied). Also, charts are (attached) proving that diabetic death rates 1983-2002 have increased steadily from the introduction of synthetic insulins in 1983. A summary of death rates before insulin was adequately purified. 1932-48. Unfortunately these rates are as high as todays death rates. Note the low death rates for the 34 years while beef insulin was the major insulin before synthetic insulin was created (U40 thru Iletin 1 - 2, and others). 1949 to 1983. The Florida Diabetic Advisory Council's (DAC) members need to change the States Insulin Recommendation to include BEEF INSULIN. (copy of recommended Policy change is attached.) ________________________________________________________ BRIEF: Note the rate columns on the attached chart,1 death rates keep climbing since synthetic insulin began to replace animal insulin2. The 2002 death rates for diabetics reached 25.4, as they were before animal insulin began to be purified around 1949. 1949 is the year when the death rates dropped from 26.4 to 16.9 and then continued to drop. Follow the records: FACTS in a NUTSHELL: 1932-1948 death rates were between 21.4-27.1 Animal Insulin (impure) 1950-1959 death rates were between 16.3-15.5 Animal Insulin (U40) 1960-1966 between 16.4-17.7 Animal Insulin (U80) 1967-1975 between 17.5-19.2 Animal Insulins (U100) 1976-1982 between 15.9-14.8 Animal Insulins were all U100 - Iletin two pork Iletin two beef and Iletin One (85% beef/15% pork mix) 1983-1998 A continual rise in the death rate between 15.5-24 as genetically engineered synthetics were being introduced, Iletin II pork and Iletin II beef was discontinued in 1995 FDA reported cloned Humulin to be the 8th in Adverse events in 199514 Iletin 1 beef/pork insulin was discontinued in 1998.3 1999-2002 Death rates continued to rise from 25.1 to 25.4 Synthetics sold at local pharmacies. Beef insulin importation was and still is allowed but most doctors refused to write the letter required by the FDA allowing their patients to import beef insulin.4 The diabetic male death rates have always been lower than the female, but since 1983 have been rising to never before recorded highs. I think it is because of their lack of ability to tolerate GE insulins. (see chartThe aqua column) As animal insulins were perfected death rates dropped to 14.9 in 1982, the year before Humulin Insulin was approved for market. This approval brought with it a continual rise in diabetic death rates to 25.4(see chartThe lavender column, note and compare the 1982 bold figure with the 2002 bold figure and the constant death rate increase in between.) ------------------------------------------------------------------------ Other Realities The Center for Disease Control's (CDC) Counting Methods Changed in 1996 and 1997 In 1996-7: 1. Diabetics were added to the disease with lower blood glucose readings. 2. This caused a large increase in diagnosed type 2's. 3. This caused the total number of diabetics to increase without scientific study to support the change. 4. Thus, fictitiously lowering the increasing diabetic death rate 5. In 1997: 1. Frequently there were 18,500,000 diabetics referred to in many articles, which included not diagnosed diabetes. 2. Only diagnosed diabetics were used to determine the death rates.{See notes above 1-4} 3. The actual count is 13,300,000 for 2002 including only the diagnosed diabetics.6 {see notes above 1-4} March 1999--Since 1980 the death rate due to diabetes has increased by 30 percent, while it has fallen for other common diseases such as cardiovascular. 7 [Note: beef insulin was available on the market until the end of 1999] Diabetes is associated with excess mortality. This excess mortality is evident in all age groups... most pronounced in young people with type 1 diabetes8. 13,300,000 diabetics/294.415,000 population = 4.5% of pop. are diagnosed diabetics. 1 M type 1s /294.415M pop. = .34% +- of diabetics are type one (7.5% of all diabetics). Approximately 5-10% of diabetics are Type One. Approximately one in every 400 to 500 children and adolescents have type 1. diabetes9. The average yearly health care cost for a person with diabetes was $13,243 in 2002 compared with $2,560 for a person without diabetes. Diabetes costs represented 11% of national health care expenditures during 2002.10 *National statistics count that each Diabetic costs 517% more than a normal person. *My cost is less than $2560 because I import beef/bovine insulin thus have fewer diabetic health problems. 1980 thru 2002: The number of hospital discharges for heart failure as the 1st listed diagnosis and diabetes as the 2nd diagnosis increased dramatically from 97,000 to 334,000 = 237,000 increase [244%]. 11 While deaths from heart failure declined for the rest of the population.11 This is what I thought would happen in 2000 when there was no longer any Beef Insulin available. #1 Synthetic insulin causes severe hypoglycemic unawareness in approximately 41% of insulin dependent diabetics.12 “'Human' insulin in the UK is still prescribed almost automatically which means that the problems which some people have are being ignored and the newly diagnosed may be suffering without realizing that their symptoms could be relieved by a change to animal insulins. We know from the people with diabetes that these problems do not just affect those who were originally on animal insulin, they are also affecting the newly diagnosed who have only used 'human' insulin. These problems fit into clearly defined categories and the results of our questionnaire to our members showed the same problems demonstrated in a prepared report by the BDA, which was never published. The first 100 people to contact the Insulin Dependent Diabetes Trust gave us the following data: 41% complained of loss of warnings of hypos 34% of extreme tiredness or 'sleeping all the time' 32% of considerable weight gain [10 kg or more] 28% of feeling unwell or depressed 24% of memory loss or confusion 9% of blood glucose levels dipping and peaking wildly” (by Jenny Hirst).12 #2 Beef Insulin rarely causes hypoglycemic unawareness. It is smooth and gentle, usually gives adequate warnings of low blood glucose and a choice of One Shot Daily depending on the patients life style. Pork insulins are a little faster than Beef but lack an adequate basal activity and less warning of hypoglycemia. However, for those that can’t take ‘synthetic’ insulin, either beef or pork at least work but Pork to a lesser degree than Beef. Pork is only 1 molecule different from a human's insulin. Beef is 3 molecules different. This is one reason it works so well. #3. When a diabetic dies from hypo unawareness and the blood glucose isn’t tested within a few hours, the cause of death is usually reported to be heart failure. Obviously, SYNTHETIC insulin has lead to this phenomena in the type 1 and possibly the type 2 if they inject insulin. #4.Logically, hypo unawareness is the most likely reason for heart failure in an otherwise healthy diabetic. #5. We Need Beef Insulin! ========================================================= History and New Insulin Science Eli Lilly and Co. claimed: 'Human' insulin was the best insulin because it was identical to the insulin made naturally by the non-diabetic pancreas. Without evidence, the pharmaceutical manufacturers sold the synthetic insulin readily by inaccurately stating, without proof that their 'human' (cloned e-coli) insulin was the best because of it's similarity to human insulin. Original statement by Eli Lilly: "All diabetics can successfully take Humulin insulin." Eli Lilly and Companies NEW STATEMENT, 20 years later: Lilly's representative, Dr. Grossman in 2003, stated to the Canadian Parliment that this isn't true. New Statement by Novo Nordisk: Novo's representative this year, 2004, also stated the same thing. Consider the deaths and increasing complications for the patients that were forced to accept the original statement. These current announcements do not revive the death and maiming that was caused by Lilly's and Novo's 20+ years of misleading information. Insulin policies need to be corrected NOW to include beef insulin at least on Florida's Recommended Insulin policy statement (attached). Recent and Current animal insulins: . U100 Iletin II Beef was discontinued in 1995. . U100 Iletin I Beef 85% / Pork 15% was discontinued in November 1998 . U100 Pork is slowly vanishing from the market place and the price has jumped from $18 to $47 since 2000. But pork, though better than synthetic, doesn’t offer near the quality of life that beef insulin offers. Hypurin Bovine/beef Insulin can be imported from CP Pharmaceuticals in Wales, UK. Click >import beef insulin From 1983-1998 death rates rose from 15.5 to 24 as cloned Human type insulin began to push animal insulin from the local pharmacies. From 1998-2002 death rates have increased from 24 to 25.4. This is as bad as way back when animal insulin had not yet been perfected, before 1948. The death rates for these supposedly pure synthetics are not acceptable. Animal insulin is 99% pure. 'Humulin' synthetic is only 97% pure.13 ======================================================== Margie Baker's Insulin History THESE NOTES RELATE TO MY EXPERIENCE WITH BEEF AND HUMAN INSULIN since 1944, age 3: Age 3-8: Beef PZI was all there was? I survived on this but felt awful. Age 8 to approximately age 33: Beef U40 isophane: I took one shot a daily. * Wonderful stuff. * Began to lead a basically normal life. Beef U80: One Shot Daily of isophane. It to was wonderful stuff and of course the dose was less.  * Back then we didn't have home blood testing.  We tested our urine for sugar and acid frequently. * On these insulins, I never had hypoglycemic unawareness.  I very successfully took U80 until it was discontinued.    Beef U100: I was desperate to find the old U80 but it had been discontinued.  It wasn't all that bad but not as good as the U40 or U80.  At the time of this change it was necessary to mix regular with the isophane but  I could not achieve the same control as I had on the U40 and U80 without adding regular.  The hypos were a little more sneaky but still, I never had hypo unawareness. U100 Beef must have been the cause of the death rates increasing 2-2.8. 85% Beef, 15% Pork:  Next the market introduced the 85% Beef, 15% Pork mix. This insulin was obviously a major cause for the lowest diabetic death rates ever recorded in 1982.  Good stuff. 85% Beef, 15% Pork, the year 1998: There was a little red warning on the Iletin I insulin box that the product would be discontinued shortly. I figured that someone else would make it. But the stores ran out at the end of the century, December 1999. I bought a 1.5 year supply. Would have bought more but that was all they had. Though the dates on the bottles expired, the insulin stayed good. The search began to find possible suppliers of beef insulin and fortunately found CP Pharmaceuticals in Wales. Humulin NPH and R: Somewhere around age 53, my doctor advised that I take Humulin NPH and R. I felt awful so I switched back to the Beef NPH and R. I immediately recovered. Age 59: Since Beef insulin was no longer sold in the stores, I was forced to again buy the Humulin. I felt like a zombie and switched back to my last bottles of Iletin. I and again immediately recovered. I wrote to Congressman Bilirakis about the deadly dilemma but all he said was that he knew nothing about the matter and thus could only help make the import process easier.? Later, I found out that he was the chairman of the Congressional Health Committee and if anyone could help, he could! His inability to understand or help made no since until I found that he was heavily funded by big pharma. Hmmm. The majority of problems IDDM patients are experiencing cannot usually be blamed on them. But rather on their inability to achieve adequate control because of the synthetic insulin's action and their attempt to achieve reasonable blood glucose directed by their doctor's instructions formulated from the American Diabetes Assocition's (ADA) Diabetic Complications Control Trial (DCCT) directives. I know this because of my own experience with Humulin insulin and various diabetic doctors use of the DCCT as well as the experiences of many of my peers. Beef and Pork insulin needs to be added back to Florida's and the world's Recommended Insulin Policy(s). ===================================================

========================================================== DIABETIC DEATH RATES CONTINUE TO RISE SINCE SYNTHETIC INSULIN STARTED IN 1983 Rates per 100,000 population 1979 to 2002 Rate=the numerator is the # deaths from diabetes and the denominator is the number of persons with diabetes in the population. CHART thousands millions death rates death rates lead Yr       Population Total Daib. dead total dead   rate all Male Female increase Yr % cod 79 33.2 1.914 14.8 12.6 16.8 622/33841= -1.8 6th 80     5.8M tot diab 34.9 1.99 15.4 1700/33200= 5 7th 81 34.6 1.978 15.1 12.7 17.3 300/34900= -0.8 7th 82 34.6 1.975 14.9 12.6 17.1 0 0 7th 83   Humulin start 36.2 2.019 15.5 12.9 18 1600/34600= 4.6 7th 84 35.8 2.039 15.2 13 17.3 ^400/36200= -0.1 7th 85 37 2.086 15.5 13.2 17.8 1200/35800 3.4 7th 86 37.2 2.105 15.5 13.2 17.7 200/37000= 5 7th 87 38.5 2.123 15.9 13.8 17.9 1300/37200= 3.5 7th 88 40.4 2.168 16.5 14.3 18.7 1900/38500= 5 7th 89 46.8 2.15 19 16.4 21.4 6400/40400= 16 7th 90 250M 47.7 2.148 19.2 16.7 21.5 900/46800= 2 7th 91 49 2.17 19.4 17.2 21.6 1300/47700= 2.7 7th 92 50 2.176 19.6 17.4 21.7 1000/49000= 2 7th 93 53.8 2.269 20.9 18.6 23.1 3800/50000= 7.6 7th 94 56.7 2.279 21.8 19.5 24 2900/53800= 5.4 7th 95 beef stopped 59.3 2.312 22.6 20.4 24.6 2600/56700= 4.6 7th 96 bg lowered 61.8 2.3147 23.3 21.3 25.2 2500/59300= 4.4 7th 97 62.6 2.3142 23.4 21.5 25.2 800/61800= 1.3 7th 98  beef/pork stop 64.8 2.337 24 22.4 25.2 2200/62600= 3.5 7th 99 68.4 2.391 25.1 23.4 26.7 3600/64800= 5.5 6th 2000    281,422,000 69.3 2.403 25.2 23.5 26.9 900/68400= 1.3 6th 2001 71.4 2.416 25.1 23.5 26.6 2000/69300= 3 6th 2002 13.3M tot diab 73.1 2.448 25.4 1800/71300= 2.5 6th Method of counting to determine who is diabetic has changed 22 year Diabetic population 2002    13,300,000 1980    5,800,000 UP 7,500,000      129% 1996 BG lowering causes the diab. population to rise, causing a fictitious diabetic epidemic.5 Lowering the BG determiner for who is a diabetic affectively reduced/disguised the stated death rates. Statistically causing far more diabetics to be counted by including pre-diabetics, making the death rates far lower than reality. 25 years of diabetic deaths compared to the other death rates, 1979-2002. 4 yr diabetic deaths before synthetic insulin 15 yr diab death 4 yr diab deaths (no beef) 20 yr diab dead 1982    34600 1998    64800 2002    73,100 2002    73100 1979    33200 1983    36200 1999    68,400 1983    36200 Up   1400  4.2% Up  28,600   79% Up 4,700   6.9% Up 36900   102% Compare 4.2% to 3.1%                    then                      Compare 102% to 21.3% 4yr all deaths 15 Yr all deaths 4 yr all deaths 20 yr all death 1982   1.975M 1998   2.34M 2002   2.45M 2002 2.45M 1979    1.914M 1983   2.02M 1999   2.39M 1983    2.02 up 61,000>    3.1% Up 320,000 16% UP 60,000   2.5% Up 430,000  21.3% 20 yr population growth =23% 1980 227,259,000 2000 281,422,000 Growth 54,163,000 = 23% 2004 population 294,415,000 Figures are from The National Center for Health Statistics http://www.cdc.gov/nchs/data/dvs/lead1900_98.pdf pg2-57 and 9-16-04 letter from Joslin's Dr H. Hall ====================================================

Florida's Insulin

Needed changes are in yellow Now in effect: Recommendation of the Diabetes Advisory Council: The Use of Human verses Animal Insulin Human insulin has become the insulin of first choice for newly diagnosed patients with diabetes and is recommended by the American Diabetes Association for patients beginning insulin therapy. The Diabetes Advisory council supports the ADA position on insulin therapy. It is important to note, as with any new medical treatment, starting or changing insulin should be done with caution and only under close medical supervision. Patients should have appropriate, close glucose monitoring to reduce or avoid the occurrence of hypoglycemia. Patients and health care professionals should work closely on disease management strategies for reducing complications. Close self-management by following a prescribed regiment, which includes blood glucose monitoring, is an essential key for successful day-to day care. Samuel E. Crockett, MD ___________________________ Recommended Change 11/5/2004: Recommended changes are in yellow Recommendation of the Diabetes Advisory Council: The Use of Human verses [and] Animal Insulin Human insulin has become the insulin of first choice for newly diagnosed patients with diabetes and is recommended by the American Diabetes Association for patients beginning insulin therapy. The Diabetes Advisory council supports the ADA position on insulin therapy. [However, if the synthetic insulins are not tolerated by the diabetic or too many shots are required daily then Beef/Bovine insulin may be recommended.] It is important to note, as with any new medical treatment, starting or changing insulin should be done with caution and only under close medical supervision. Patients should have appropriate, close glucose monitoring to reduce or avoid the occurrence of hypoglycemia. Patients and health care professionals should work closely on disease management strategies for reducing complications. Close self-management by following a prescribed regiment, which includes blood glucose monitoring, is an essential key for successful day-to day care. [Brittle Juvenile diabetics should strive for no lower than 7.5 A1c or higher than 8.8 A1c to avoid hypoglycemic unawareness. This type diabetic must be instructed concerning the Somogyi effect caused by too many hypoglycemic reactions.] Submitted 9/1/2004 and again 11/5/2004 By: Marjorie A. Baker, member Diabetic Advisory Council Ph: 727-938-6572

===================================================== SUMMARY: * 1922-1948 death rates were 21.4-27.1 when animal insulin wasn't very pure * 1949-1982 death rates were 19.2-14.8, an all time low for 34 years while beef insulin was the major insulin used. * 1999-2002 varied web sites from the National Center for Health Statistics * Compare the DEATH RATES 1949-82 to 1982-2002 & 1932-1949. * Be mindful of the 41% hypoglycemic unawareness caused by the synthetics. Hypoglycemic unawareness is rarely caused by beef insulin. * In 1996, blood glucose rates for determining who is diabetic were lowered causing death rates to appear lower because of the increase in diabetics counted that are not inclined to die from diabetes. Even so by 2002 death rates were near the all time high for diabetics. Consider what they would be had the blood glucose rates not changed. Death caused by hypo unawareness, other wise known as insulin reaction, is usually diagnosed as heart failure and is listed as the 1st cod. Diabetic deaths determined to be heart failure has increased 244% since the marketing of genetically engineered synthetic insulin began, thus hiding the real cause of death, which is GE insulin. The Death rate for diabetes started to slowly rise in 1983 as people began injecting GE ‘human insulin’. In 1995, Iletin 2 Beef insulin was no longer manufactured. Also, in 1995, Human Insulin was reported to be #8 on the FDA's Adverse Drug Experience Report.14 There aren't enough insulin taking diabetics in the US to cause GE insulin to be included in the FDA's top 10 adverse drug report unless the drug was horrifically bad. Then in 1999 Iletin 1, which was 85% beef and 15% pork, insulin was no longer manufactured. The local pharmacies ran out by the end of the century. Iletin II Pork insulin is still available if ordered. Lilly's animal insulin manufacturing plant was torn down in November 1999. The beef and pork mix remained available until supplies ran out. The supply of pork as of the end of 2004 is still available in the United States. Simple logic will tell you that the beef ran out first because of its popularity but the pork has still not sold out. One doesn’t need to be a rocket scientist to interpret the obvious death rate indicators. Synthetic insulin is the obvious cause for most of the heart failure because 41% can’t tell when they are hypo and more and more began to just plain drop dead from insulin reaction and their heart, of course, fails to keep beating --- called heart failure. The cause of death is listed as heart failure instead of diabetic hypo-unawareness. This would not be included in the diabetic death ratios listed on the charts because diabetes is not reported as the 1st cod. However, since synthetic insulin hit the market in 1983 the death rates have soared as the diabetics were switched from animal insulin to synthetic insulin. The DCCT also helped achieve the unreasonably hi and rising death rates. The method of determining who is diabetic greatly increased our numbers with healthy type 2's that rarely die of diabetes. This should have reduced the death rates but the rates rose anyway. The unreasonable 102% escalation in the diabetic deaths from 1983 to 2002 see chart (lavender rate column) is ALARMING by itself. Statistics obviously prove that hypoglycemic unawareness and other unnecessary complications are caused by the synthetic genetically similar human insulins. Using just the rising general diabetic deaths of 102% from 1983 to 2002 then adding to it 244% of the diabetics that have died from heart failure is ALARMING! The percentages and death rates were far lower prior to 1983 when only animal insulin was injected by diabetics. * That’s 36,200 general diabetic deaths in 1983 + 97,000 diabetics with heart failure = 133,200 people in 1983. * Then 73,100 general diabetic deaths + 334,000 diabetics with heart failure = 407,100 people in 2002. * Formula: 407,100-133,200=273,900 an increase of 206% for both (over a quarter of a million human beings). The population is not going up respectively. The deaths from diabetes are out of control [see chart]. It's the synthetic insulin folks. Were you aware that in 1921 Dr Banting made the 1st insulin from a dog’s pancreas? It helped reduce the diabetic dog’s blood glucose but not very well. Then Dr Banting tried beef insulin on the test dogs and their blood glucose improved considerably. Please apply the logic to beef insulin for people. The reintroduction of beef insulin is obviously not on the slate because most doctors blame the diabetic patients for causing their maladies. Their need for beef insulin is not even considered. Then when the patients ask for a letter so they can import the bovine/beef insulin they are almost always denied. Thus their suffering continues. As the statistics prove, an unreasonable and increasing number of people lose their lives either from hypo unawareness or other complications that occur much less frequently when these needy patients inject beef insulin. For the brittle diabetic, beef insulin is like a poor man’s pump with only one or 2 shots daily required, considering the type of bovine insulin chosen. The pump is too expensive for nearly all un-insured patients. It is pretty tacky to inject and then have to wear an injected tube all day. And then they need to be a mathmatition to calibrate the thing. On top of that the cost is outragious. Infection is frequent, and it is also no fun when the pump malfunctions. But if the patient knew how much easier diabetes is to control with beef insulin, then few if any would choose an insulin pump. However, their doctors probably will refuse to give them the letter of necessity that is required so that they can import beef insulin. When their patients ask or when the patient is responding poorly to synthetic insulins, the doctor should feel confident in recommending beef insulin importation. Beef and Pork Insulin should be on the DAC’s Recommended Insulin statement. It has proven itself to be the best insulin ever made (see my chart). Death rates were 12.2 to 19.2 for 34 years of animal insulin use from 1949-1983. Death rates rose from 15.5 straight up to 25.4 after synthetic insulin began to be marketed from 1983 to the present time. Death rates prove that modern science has gone backwards to the days of poorly refined animal insulin, 1922-49. Today, many patients choose a pump rather than 2 Lantus injections and 3 bolus injections before each meal + extra bolus injections for hyperglycemia and/or snacks. Some people require 5 to 8 shots daily thus they choose the pump if they can afford it. People aren’t pincushions. Continual injections have complications also. Beef insulin should again be included as a patient’s choice and doctor’s suggestion. Besides the lack of necessity for continual injections, the main benefit of beef insulin is its mildness, its rare hypo unawareness incidence and fewer injections. One Shot Daily is possible. Death rates have Infection is frequent, and it is also no fun when the pumps malfunction. Death rates have escalated indicating that modern diabetic science has gone backwards to the early days, 1922-49. Attached (see Insulin Policy below) is the change I am requesting for the Diabetic Advisory Council’s Recommended Insulin statement. Please advise me, of any questions or objections. Margie Baker Diabetic Type One Org floridacracker@ij.net ===================================== CANARIES in the MINE SHAFT By: Margie Baker 9/17/2004 We insulin dependent diabetics were the 1st people used as ‘CANARIES in the MINE SHAFT’ to test the adequacy or inadequacy of the 1st e-coli cloned medicine. Like the canaries we are dropping dead prematurely (see chartS). Unfortunately, neither the miners nor the canaries have left the mine shaft. The miners are only just beginning to admit to the problems they are having trying to keep the canaries alive via cloned insulin that does have a tiny bit of e-coli left behind13. Even going so far as pumping the stuff thru an infection causing and occasionally malfunctioning pump, hoping the canaries get the nack and learn the necessary math variables. The disease frequently has a mind of its own, especially when it comes to GE insulin. The miners continue to search for a true synthetic basal insulin but to date, only beef insulin (not synthetic) has proven itself worthy. I don't know about you but the choice of an insulin pump compared to one or 2 shots daily of beef isophane and neutral is a no brainer. The facts are clear but never acknowledged by the medical community. Beef insulin has always been better than synthetic insulin.

Sources & Footnotes

1. My attached chart covers 1979 to 2002. Figures are available and are included in my article from 1932 to 2002 for diabetes from The National Center for Health Statistics. 2.Consider 21.4 - 27.1 death rates for the years 1932-1948 when animal insulin wasn’t very pure. Compare the steady rise in death rates on the chart from 15.5 to 25.4 for the years 1983 to 2002 while synthetic insulin was invading and then took over the market via ill informed medical advice. Then consider the far lower death rates 19.2 - 14.8 for the years 1949 -1982, 34 years. The 34 yr. death rates when patients were only injecting properly purified animal insulin were as low as they have ever been. This indicates absence of any valid reason to start anyone on the synthetics that have never been proven to be as good as animal insulin (See attached charts). The original tests were against pork insulin. They revealed GE insulin's tendency to cause hypoglycemic unawareness and other defencies. Both animal and synthetic insulins are pure (folks, this is medical jargon). But animal insulin is 2% purer than Humulin, the 1st GE insulin. Humulin was found to have 4ppm remaining e-coli bacteria left behind in the finished GE product.13 3. National Center for Health Statistics http://www.cdc.gov/nchs/data/dvs/lead1900_98.pdf Pg2-55 and a letter from Joslin's Dr H. Hall 9/16/04. 4. Frequently Asked Questions about Importing Beef Insulin for Personal Use http://www.fda.gov/cder/drug/beefinsulin/default.htm 5. National Center for Chronic Disease Prevention and Health Promotion, Diabetes Public Health Resource, News & Information, CDC Statements on Diabetes Issues [2004], http://www.cdc.gov/diabetes/news/class.htm#1. scroll to #2 for diagnosis, #7 Implications, #8 no scientific study. Diabetes Care 1997; 20(7):1183-97. 6. National Center for Chronic Disease Prevention and Health Promotion, Chronic Disease Prevention; http://www.cdc.gov/diabetes/statistics/prev/national/figpersons.htm, http://diabetes.about.com/od/aboutdiabetes/a/2002_US_stats.htm scroll down 1/3 page to Diabetes Is a Growing Public Health Problem 7. 2004, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, (617) 732-2400. Latest News/Press releases, http://www.joslin.harvard.edu/news/inthenews.shtml scroll 4/5th down the page to: Diabetes Mortality rapidly on the rise. 8. BMJ 2001;322:1389-1393 (9 June),June 10, 2001, Editorial by Williams, Nick A Roper, NHS research training fellow, http://bmj.bmjjournals.com/cgi/content/abstract/322/7299/1389,see Conclusion scroll to 1/4 pg down Correspondence to: N A Roper n.a.roper@ncl.ac.uk 9. Diabetes Public Health Resource, National Center for Chronic Disease Prevention and Health Promotion, http://www.cdc.gov/diabetes/faq/basics.htm#3 Frequently Asked Questions. Scroll to: What are the types of diabetes? Type 1 diabetes, which was previously called insulin-dependent diabetes mellitus (IDDM) or juvenile-onset diabetes, may account for 5% to 10% of all diagnosed cases of diabetes 10. National Center for Health Statistics (NCHS), http://diabetes.about.com/od/aboutdiabetes/a/2002_US_stats.htm, http://www.cdc.gov/nccdphp/aag/aag_ddt.htm 11. Chart: Data & Trends, Diabetes Surveillance System, Hospitalization for Heart Failure as First-Listed Diagnosis, Number (in Thousands) of Hospital Discharges with Heart Failure as First-Listed Diagnosis and Diabetes as Secondary Diagnosis, United States, 1980-2002 http://www.cdc.gov/diabetes/statistics/cvdhosp/hf/table1link.htm [Note: when one drops dead for no findable cause, their heart stops thus [‘Heart Failure’] 12.INSULIN DEPENDENT DIABETES TRUST (IDDT), CONTROVERSY CORNER,(Jenny Hirst) Co-Chairman of IDDT, IDDT, PO Box 294, Northampton NN1-4XS, England 13. Galenics of Insulin, The Physico-Chemical and Pharmaceutical Aspects of Insulin. With the collaboration of B Skelbaek-Pedersen, L Langkjaer, U Damgaard, H Ege, S Havelund, L.G. Heding, K.H. Jorgensen, J Lykkeberg, J Markussen, M Pingel, E Rasmussen. Pub. Jens Brange, M.Sc, Novo Research Instute, Novo Alle, 2880 Bagsvaerd, Denmark, Berlin, Heidelberg, NY, London, Paris, Tokyo, printed in Germany (copyright). Page 79 chart shows pork insulin 99% pure & Human insulin to be 97% pure. The GE type insulin had 4ppm of e-coli bacteria left in the finished product and that stuff multiplies fast! 14. Center for Drug Evaluation and Research, Food and Drug Administration. 1995, Annual Adverse Drug Experience Report: Deanne E Knapp, Janet I Robinson, and Annie L Britt Surveillance and Data Processing Branch Division of Pharmacovigilance and Epidemiology Office of Epidemiology and Biostatistics Contact To Print, set printer for landscape. The charts are wide.